DRIED NANOPARTICLE COMPOSITIONS

Abstract: provided herein are dried compositions and methods for preparing such compositions for use in delivery of a nucleic acid to a subject. the dried composition may comprise a lipid carrier, wherein the lipid carrier is a nanoemulsion comprising a hydrophobic core, optionally one or more inorganic nanoparticles and one or more lipids, one or more nucleic acid, and at least one cryoprotectant. methods of using these dried compositions for treatment are also provided.

Inventor(s): Steven Gregory Reed, Amit Praful Khandhar, Darrick Albert Carter

CPC Classification: A61K9/1075 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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