LIQUID BOTULINUM TOXIN FORMULATION AND USE THEREOF

Abstract: the present invention relates to a liquid botulinum toxin formulation comprising: (i) botulinum toxin, (ii) a stabilizing protein such as human serum albumin, (iii) a chelating agent (e.g., edta) or phosphate, and optionally (iv) a salt of calcium, magnesium or zinc, (v) a tonicity agent and/or (vi) a buffering agent. in addition, the present invention relates to the use of the liquid botulinum toxin formulation for therapeutic and cosmetic treatments.

Inventor(s): Karl-Heinz EISELE, Klaus FINK, Harold V. TAYLOR, Claudia JATZKE, Katja KÜHBACH

CPC Classification: A61K8/66 (Enzymes)

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