OLIGONUCLEOTIDE PRODUCTION METHOD

Abstract: as a solid phase synthesis method of an oligonucleotide that enables cleavage of a synthesized oligonucleotide even under mild conditions, a solid phase synthesis method of an oligonucleotide, including a step of carrying a nucleotide derivative represented by the formula (i):

Inventor(s): Yoshiyuki Hari, Yasufumi Fuchi, Yuta Ito, Kazuki Yamamoto

CPC Classification: C07H21/04 (SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS (derivatives of aldonic or saccharic acids , ; aldonic acids, saccharic acids , ; cyanohydrins ; glycals ; compounds of unknown constitution ; polysaccharides, derivatives thereof ; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification ; sugar industry ))

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