20250154172. Prmt5 Inhibitors And Use (Gilead Sciences, Inc.)
PRMT5 INHIBITORS AND USES THEREOF
Abstract: the present disclosure relates generally to compounds that inhibit prmt5. the disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through inhibiting prmt5. the disclosure further relates to the use of the compounds for the treatment of a disease or condition associated with chromosome 9p21 deletion or mtap null. the disclosure further relates to the use of the compounds for the treatment of cancers.
Inventor(s): Megan K. Armstrong, Elbert Chin, Chienhung Chou, Laurent P. Debien, Yifan Deng, Joshua D. Farr, Chao-I Hung, Benjamin J. June, Shaina V. Nguyen, Daniel Roa, Katie A. Spence, Zheng-Yu Yang
CPC Classification: C07D519/00 (HETEROCYCLIC COMPOUNDS (macromolecular compounds ))
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- Patent Applications
- Gilead Sciences, Inc.
- CPC C07D519/00
- Megan K. Armstrong of San Francisco CA US
- Elbert Chin of San Mateo CA US
- Chienhung Chou of Dublin CA US
- Laurent P. Debien of San Francisco CA US
- Yifan Deng of Milpitas CA US
- Joshua D. Farr of Mountain View CA US
- Chao-I Hung of San Mateo CA US
- Benjamin J. June of San Francisco CA US
- Shaina V. Nguyen of Yorba Linda CA US
- Daniel Roa of Foster City CA US
- Katie A. Spence of San Francisco CA US
- Zheng-Yu Yang of Palo Alto CA US