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20250154155. Synthetic Method Of 7,8-dihyd (HUTCHMED LIMITED)

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SYNTHETIC METHOD OF 7,8-DIHYDRO-2H-CYCLOPENTA[4,5]PYRROLO[1,2-A]PYRAZIN-1(6H)-ONE COMPOUNDS

Abstract: the present invention relates to a method of synthesizing a 7,8-dihydro-2h-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-1(6h)-one compound and an analog thereof. the method is well suited for large-scale industrial production because of its simple steps, simple and safe reaction operations, and easily separated and purified related intermediates.

Inventor(s): Bo LIU, Chongfeng GE, Chenguang FAN, Chuanguo WANG

CPC Classification: C07D487/04 (Ortho-condensed systems)

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