DECELLULARIZED MUSCLE MATRICES AND METHODS FOR MAKING AND USING SAME

Abstract: decellularized muscle matrices are provided for use as implants and grafts to repair, regenerate, supplement, reinforce and replace muscle tissue. the decellularized muscle matrices are derived from muscle tissue having preserved extracellular matrix components, retained muscle-forming potential, and from which immunogenic components have been removed. the decellularized muscle matrices are produced in various physical forms and combinations. methods for making and using the decellularized muscle matrices are also provided.

Inventor(s): Emily Imming, Yen-Chen Huang, Eric J. Semler, Roman Shikhanovich, Marc Long

CPC Classification: A61L27/3604 (METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed ; preserving, e.g. sterilising, food or foodstuffs ; preparations for medical, dental or toiletry purposes ))

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