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20250152726. Nucleic Acid-polypep (Avidity Biosciences, .)

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NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF

Abstract: disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.

Inventor(s): Andrew John GEALL, Venkata Ramana DOPPALAPUDI, Joel Daniel ARIAS, David Sai-Ho CHU, Michael Caramian COCHRAN, Rob BURKE, Philip KOVACH, Barbora MALECOVA

CPC Classification: A61K47/6807 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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