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20250152724. Antibody Conjug (R.P. Scherer Technologies, LLC)

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ANTIBODY CONJUGATES SPECIFIC FOR MUCIN-1 AND METHODS OF USE THEREOF

Abstract: the present disclosure provides antibody conjugates (e.g., antibody-drug conjugates (adcs)) specific for muc1. the disclosure also encompasses methods of production of such conjugates, as well as methods of using the same. also provided are compositions that include the adc of the present disclosure, including in some instances, pharmaceutical compositions. in certain aspects, provided are methods of using the adc that include administering to an individual having a cell proliferative disorder a therapeutically effective amount of the adc of the present disclosure.

Inventor(s): David RABUKA, Penelope M. DRAKE, Yun Cheol KIM, Robyn M. BARFIELD, Maxine BAUZON, Ayodele OGUNKOYA, Stepan CHUPRAKOV

CPC Classification: A61K47/68031 ({Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates})

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