NEW CARBOHYDRATE DERIVATIVES AS MIMETICS OF BLOOD GROUP A AND B ANTIGENS

Abstract: the present invention relates to new carbohydrate derivatives with activity as mimetics of blood group a and b antigens. the present invention also relates to a method for preparing said carbohydrate derivatives and to a glycoconjugate comprising them bound to a polymeric support. the invention also relates to the use of the glycoconjugates for inhibiting and/or removing anti-a and/or anti-b antibodies from blood and blood derivatives and by-products, and, in particular to their use for avoiding rejection in subjects undergoing in organ transplant or haemolytic reactions in blood transfusions from incompatible donors.

Inventor(s): Daniel BELLO GIL, Sara OLIVERA ARDID, Yara FERRERO ALVES, Nailia RAMILEVNA KHASBIULLINA

CPC Classification: A61K47/549 ({Sugars, nucleosides, nucleotides or nucleic acids})

Search for rejections for patent application number 20250152720