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20250152578. Stabilizing Camptothecin P (Ipsen Biopharm Ltd.)

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Stabilizing Camptothecin Pharmaceutical Compositions

Abstract: irinotecan phospholipid liposomes with improved storage stability are provided. with related methods of treatment and manufacture. the irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-pc) during storage. and prior to administration to a patient.

Inventor(s): Daryl C. Drummond, Dmitri B. Kirpotin, Mark E Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien

CPC Classification: A61K31/4745 (PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms ; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles ; soap compositions ))

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