COBALT-CHROMIUM ALLOY STENT AND DRUG ELUTING STENT

Abstract: a cobalt-chromium alloy stent comprising several main body units, wherein each main body unit is composed of several supporting rings connected by flexible ribs and the adjacent main body units are connected by several connecting ribs. a drug eluting stent comprising the cobalt-chromium alloy stent and a drug coating containing arsenic trioxide and tacrolimus. the drug release curves of the two composite drugs of arsenic trioxide and tacrolimus used in the present invention are adjusted, so that the inflammatory response of vascular endothelial cells and the proliferation behavior of vascular smooth muscle cells are effectively inhibited, and the vascular restenosis rate is reduced.

Inventor(s): Dongyun HAO, Bo YU, Kefei DOU, Xin SHEN, Bili ZHANG, Fugui HE, Lifeng ZHOU, Xiaoyi MA

CPC Classification: A61F2/88 (the wire-like elements formed as helical or spiral coils (forming a net-like or mesh-like structure ))

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