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20250152033. Support Diagnosis N (NAGASAKI UNIVERISTY)

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SUPPORT FOR DIAGNOSIS OF NEUROPSYCHIATRIC SLE BY MEANS OF HEAD MRI

Abstract: the present invention provides a method for obtaining an indicator for diagnosing whether a subject is an sle patient or an npsle patient. the method includes: (1) preparing head mri images of sle patients and npsle patients; (2) gradually changing a color tone of each of the head mri images; (3) detecting and counting white connected components and black connected components generated in response to color tone changes; (4) obtaining a scatter diagram of times of generation and disappearance of the white connected components and black connected components based on the a result of the detecting and counting (3); (5) verifying whether there is a significant difference in any of image features between sle patients and npsle patients, the image features being obtained from the scatter diagram; and (6) identifying, as the indicator, an image feature in which a significant difference is recognized.

Inventor(s): Kayoko URASHIMA, Kunihiro ICHINOSE, Hideki ISHIMARU, Masao UEKI

CPC Classification: A61B5/055 (involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging)

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