19013094. Methods for Detecting Renal Disease (IDEXX Laboratories, Inc.)
Methods for Detecting Renal Disease
Organization Name
Inventor(s)
Mahalakshmi Yerramilli of Falmouth ME US
Edward Obare of Westbrook ME US
John Joseph Quinn of Falmouth ME US
Murthy VSN Yerramilli of Falmouth ME US
Methods for Detecting Renal Disease
This abstract first appeared for US patent application 19013094 titled 'Methods for Detecting Renal Disease
Original Abstract Submitted
Methods for determining renal function in an animal subject, the method including measuring the concentration of β-ammoisobutyric acid (β-amino isobutyrate) (BAIB) in patients samples and determining the presence, likelihood, or progression of kidney disease as a result of structural damage, or mortality associated with kidney disease. The methods also include measuring the concentration of BAIB in combination is symmetrical dimethyl arginine (SDMA) and determining kidney disease based upon the concentrations of BAIB and SDMA in the samples. Anti-BAIB antibodies, BAIB-conjugates, and assay methods using the antibodies and conjugates are also disclosed.