Jump to content

19002083. POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Vanderbilt University)

From WikiPatents

POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4

Organization Name

Vanderbilt University

Inventor(s)

Craig W. Lindsley of Brentwood TN US

Darren W. Engers of Brentwood TN US

Kayla J. Temple of Spring Hill TN US

Alison R. Gregro of Mount Juliet TN US

Alexa E. Richardson of Nashville TN US

Madeline F. Long of Nashville TN US

POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4

This abstract first appeared for US patent application 19002083 titled 'POSITIVE MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4

Original Abstract Submitted

Deuterium-labeled 4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)oxy)piperidines substituted with pyrrolo[3,4-b]pyridin-5-one, furo[3,4-b]pyridin-5(7H)-one, or [1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one are positive allosteric modulators of the muscarinic acetylcholine receptor M(mAChR M) and may have use in treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction.

Cookies help us deliver our services. By using our services, you agree to our use of cookies.