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19000208. ENGINEERED ANTIGEN PRESENTING CELLS AND USES THEREOF (Massachusetts Institute of Technology)

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ENGINEERED ANTIGEN PRESENTING CELLS AND USES THEREOF

Organization Name

Massachusetts Institute of Technology

Inventor(s)

Feng Zhang of Cambridge MA US

Blake Lash of Cambridge MA US

Daniel Strebinger of Cambridge MA US

ENGINEERED ANTIGEN PRESENTING CELLS AND USES THEREOF

This abstract first appeared for US patent application 19000208 titled 'ENGINEERED ANTIGEN PRESENTING CELLS AND USES THEREOF

Original Abstract Submitted

Described herein are engineered antigen presenting cells that can be capable of modulating a target T-cell in a T-cell antigen specific manner. In some embodiments, the engineered APCs can include a modified antigen presentation pathway. Also described herein are methods of making and using the engineered antigen presenting cells.

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