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18960947. COMPOSITIONS AND METHODS FOR SAMPLE PROCESSING (10x Genomics, Inc.)

From WikiPatents


COMPOSITIONS AND METHODS FOR SAMPLE PROCESSING

Organization Name

10x Genomics, Inc.

Inventor(s)

Benjamin Hindson of Pleasanton CA US

Christopher Hindson of Pleasanton CA US

Michael Schnall-levin of Palo Alto CA US

Kevin Ness of Pleasanton CA US

Mirna Jarosz of Mountain View CA US

Donald Masquelier of Tracy CA US

Serge Saxonov of Oakland CA US

Landon Merrill of Pleasanton CA US

Andrew Price of Dublin CA US

Paul Hardenbol of San Francisco CA US

Yuan Li of Dublin CA US

COMPOSITIONS AND METHODS FOR SAMPLE PROCESSING

This abstract first appeared for US patent application 18960947 titled 'COMPOSITIONS AND METHODS FOR SAMPLE PROCESSING

Original Abstract Submitted

This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.

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