18940045. PHASE-BASED OPTORETINOGRAPHY USING TISSUE VELOCITY (THE REGENTS OF THE UNIVERSITY OF CALIFORNIA)
PHASE-BASED OPTORETINOGRAPHY USING TISSUE VELOCITY
Organization Name
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor(s)
Robert J. Zawadzki of Davis CA US
Kari V. Vienola of Davis CA US
PHASE-BASED OPTORETINOGRAPHY USING TISSUE VELOCITY
This abstract first appeared for US patent application 18940045 titled 'PHASE-BASED OPTORETINOGRAPHY USING TISSUE VELOCITY
Original Abstract Submitted
Phase-based optoretinography (ORG) is performed using tissue velocity obtained from a modified optical coherence tomography (OCT) system. A swept-source generated OCT A-scan is used to assemble a 2-dimensional profile of the retinal tissue (B-scan) by laterally scanning the imaging beam. These B-scans can be taken at multiple time-points and assembled into a M-scan, which displays motion of a particular cross-section of retinal tissue (after correction for bulk motion). The method captures the changes between each timestep of the M-scan to deduce tissue velocities of the COST, ROST, and IS/OS, among others. An initial contraction of outer segments is detected in outer segments, followed by an elongation shortly thereafter. The tissue velocity measurements can be used to infer retinal dysfunction without the need for costly and computationally expensive scans using adaptive optics.