18912388. POLYMERIC VACCINE FOR OPIOID ADDICTION (THE JOHNS HOPKINS UNIVERSITY)
POLYMERIC VACCINE FOR OPIOID ADDICTION
Organization Name
Inventor(s)
David Scott Wilson of Baltimore MD US
Sandeep Kumar of Baltimore MD US
POLYMERIC VACCINE FOR OPIOID ADDICTION
This abstract first appeared for US patent application 18912388 titled 'POLYMERIC VACCINE FOR OPIOID ADDICTION
Original Abstract Submitted
Disclosed herein are immune activating conjugates with immunogenic carrier proteins coupled to hapten and immune cell receptor agonist-containing polymers. The polymers promote uptake by B cells, enabling intracellular immune cell receptor activation and formation of long-lived antibody-secreting cells. In some aspects, disclosed herein in is a conjugate comprising an immunogenic carrier protein coupled to a polymer, wherein the polymer includes: i) a first monomeric unit comprising a first monomer coupled to a hapten, and ii) a second monomeric unit comprising a second monomer coupled to an immune cell receptor agonist.