18838389. METHODS FOR IDENTIFYING RISK OF AUTISM (The Johns Hopkins University)
METHODS FOR IDENTIFYING RISK OF AUTISM
Organization Name
Inventor(s)
Andrew Paul Feinberg of Baltimore MD US
Heather Volk of Baltimore MD US
Jason Ira Feinberg of Baltimore MD US
Rose Schrott of Baltimore MD US
METHODS FOR IDENTIFYING RISK OF AUTISM
This abstract first appeared for US patent application 18838389 titled 'METHODS FOR IDENTIFYING RISK OF AUTISM
Original Abstract Submitted
The invention provides herein epigenetics changes identified in differentially methylated regions (DMRs) of DNA of a father that are associated with the risk for an offspring having autism spectrum disorder (ASD). The invention further provides methods of determining a risk of having an offspring with ASD, methods of diagnosing ASD in a subject, and methods of determining an association between exposure to an environmental factor in a subject and an increased risk of having an offspring with ASD. The invention also provides a kit for determining whether a subject has or is at risk of having or inheriting a risk of having ASD.