18826309. ANTIMONY CHELATES FOR TARGETED AUGER THERAPY AND IMAGING DIAGNOSTICS (Wisconsin Alumni Research Foundation)
ANTIMONY CHELATES FOR TARGETED AUGER THERAPY AND IMAGING DIAGNOSTICS
Organization Name
Wisconsin Alumni Research Foundation
Inventor(s)
Jonathan W. Engle of Middleton WI (US)
Nikki Thiele of Kingston TN (US)
Briana R. Schrage of Knoxville TN (US)
Md Faizul Islam of Knoxville TN (US)
ANTIMONY CHELATES FOR TARGETED AUGER THERAPY AND IMAGING DIAGNOSTICS
This abstract first appeared for US patent application 18826309 titled 'ANTIMONY CHELATES FOR TARGETED AUGER THERAPY AND IMAGING DIAGNOSTICS
Original Abstract Submitted
Antimony (Sb) chelates for use in targeted auger therapy and imaging diagnostics are provided. Also provided are methods of treating a subject in need of treatment using the antimony chelates. The chelates comprise a chelating ligand that binds an Sb radionuclide in a +5-oxidation state, such as Sb and Sb. The chelating ligand renders the Sb radionuclide stable and inert in vivo and enables the conjugation of the chelate to a biological targeting vector.