18814313. ARTIFICIAL INTELLIGENCE-BASED MANY-TO-MANY BASE CALLING (ILLUMINA, INC.)
ARTIFICIAL INTELLIGENCE-BASED MANY-TO-MANY BASE CALLING
Organization Name
Inventor(s)
Anindita Dutta of San Francisco CA US
Gery Vessere of San Francisco CA US
Dorna Kashefhaghighi of Menlo Park CA US
Kishore Jaganathan of San Francisco CA US
Amirali Kia of San Mateo CA US
ARTIFICIAL INTELLIGENCE-BASED MANY-TO-MANY BASE CALLING
This abstract first appeared for US patent application 18814313 titled 'ARTIFICIAL INTELLIGENCE-BASED MANY-TO-MANY BASE CALLING
Original Abstract Submitted
The technology disclosed relates to artificial intelligence-based base calling. The technology disclosed relates to accessing a progression of per-cycle analyte channel sets generated for sequencing cycles of a sequencing run, processing, through a neural network-based base caller (NNBC), windows of per-cycle analyte channel sets in the progression for the windows of sequencing cycles of the sequencing run such that the NNBC processes a subject window of per-cycle analyte channel sets in the progression for the subject window of sequencing cycles of the sequencing run and generates provisional base call predictions for three or more sequencing cycles in the subject window of sequencing cycles, from multiple windows in which a particular sequencing cycle appeared at different positions, using the NNBC to generate provisional base call predictions for the particular sequencing cycle, and determining a base call for the particular sequencing cycle based on the plurality of base call predictions.