HYDROGEL-FORMING SYSTEMS INCLUDING BIOLOGICALLY INNOCUOUS BUFFER

Organization Name

Inventor(s)

Nicolas Ball-jones of Minneapolis MN (US)

Joseph Thomas Delaney, Jr. of Minneapolis MN (US)

HYDROGEL-FORMING SYSTEMS INCLUDING BIOLOGICALLY INNOCUOUS BUFFER

This abstract first appeared for US patent application 18805710 titled 'HYDROGEL-FORMING SYSTEMS INCLUDING BIOLOGICALLY INNOCUOUS BUFFER

Original Abstract Submitted

In some aspects, the present disclosure provides a system for forming a hydrogel composition that comprises (a) a first reservoir containing a reactive polymer that comprises a plurality of first reactive groups; (b) a second reservoir containing a multifunctional compound that comprises a plurality of second reactive groups, the second reactive groups reacting with the first reactive groups to form covalent bonds at a pH greater than 7.4; and (c) a third reservoir containing a biologically innocuous buffer having a pH in a range of 8 to 12. Other aspects of the present disclosure pertain methods of treatment using such systems.