18799673. CELL-PENETRATING PEPTIDES FOR ANTISENSE DELIVERY (MASSACHUSETTS INSTITUTE OF TECHNOLOGY)
CELL-PENETRATING PEPTIDES FOR ANTISENSE DELIVERY
Organization Name
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventor(s)
Justin M. Wolfe of Cambridge MA US
Colin M. Fadzen of Cambridge MA US
Zi-Ning Choo of Cambridge MA US
Rebecca L. Holden of Cambridge MA US
Gunnar J. Hanson of Cambridge MA US
Bradley L. Pentelute of Cambridge MA US
CELL-PENETRATING PEPTIDES FOR ANTISENSE DELIVERY
This abstract first appeared for US patent application 18799673 titled 'CELL-PENETRATING PEPTIDES FOR ANTISENSE DELIVERY
Original Abstract Submitted
Provided herein are oligonucleotides, cell penetrating peptides, and peptide-oligonucleotide-conjugates. Also provided herein are methods of treating a muscle disease, a viral infection, or a bacterial infection in a subject in need thereof, comprising administering to the subject oligonucleotides, peptides, and peptide-oligonucleotide-conjugates described herein.
Categories:
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Justin M. Wolfe of Cambridge MA US
- Colin M. Fadzen of Cambridge MA US
- Zi-Ning Choo of Cambridge MA US
- Rebecca L. Holden of Cambridge MA US
- Monica Yao of Cambridge MA US
- Gunnar J. Hanson of Cambridge MA US
- Bradley L. Pentelute of Cambridge MA US
- A61K47/65
- A61K31/713
- A61K47/64
- C12N15/11
- C12N15/113
- CPC A61K47/65