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18728193. DETECTION AND LOCALIZATION OF INTERNAL BLEEDING (VANDERBILT UNIVERSITY)

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DETECTION AND LOCALIZATION OF INTERNAL BLEEDING

Organization Name

VANDERBILT UNIVERSITY

Inventor(s)

Seth Karp of Nashville TN US

Leo Pavliv of Cary NC US

Jerri Rook of Nashville TN US

Andrew Vila of Nashville TN US

DETECTION AND LOCALIZATION OF INTERNAL BLEEDING

This abstract first appeared for US patent application 18728193 titled 'DETECTION AND LOCALIZATION OF INTERNAL BLEEDING

Original Abstract Submitted

Systems, methods, and kits useful for detecting and locating internal bleeding, such as gastrointestinal bleeding, during active or inactive bleeding. In some embodiments, the systems, methods, and kits make use of a single photon emission computed tomography (SPECT) tracer. The kit for preparing a technetium-99m (99mTc)-labeled composition for targeting an injured site in a blood vessel, comprising: -a conjugated human fibrinogen, wherein the human fibrinogen is bonded to a chelating agent selected from the group consisting of diethylene triamine pentaacetate (DTPA) dianhydride.

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