18724564. CYSTEAMINE AND/OR CYSTAMINE PRODRUGS (THE REGENTS OF THE UNIVERSITY OF CALIFORNIA)
CYSTEAMINE AND/OR CYSTAMINE PRODRUGS
Organization Name
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor(s)
Ranjan Dohil of San Diego CA (US)
Carlo Ballatore of San Diego CA (US)
CYSTEAMINE AND/OR CYSTAMINE PRODRUGS
This abstract first appeared for US patent application 18724564 titled 'CYSTEAMINE AND/OR CYSTAMINE PRODRUGS
Original Abstract Submitted
The disclosure provides for cysteamine prodrugs, pharmaceutical compositions made thereof, and methods thereof including the treatment of any disease or disorder in a subject that can benefit from one or more of the bioprotective effects of cysteamine, including but not limited to, binding of cystine, reducing oxidative stress, increasing adiponectin levels and/or increasing brain-derived neurotrophic factors. Examples of such disease and disorders, include but are not limited to, cystinosis, and fatty liver diseases including non-alcoholic steatohepatitis (NASH).