18695574. Supermere Nanoparticles and Methods of Isolation and Use Thereof (Vanderbilt University)
Supermere Nanoparticles and Methods of Isolation and Use Thereof
Organization Name
Inventor(s)
Robert J. Coffey, Jr. of Nashville TN US
Jeffrey Franklin of Nashville TN US
Dennis Jeppesen of Nashville TN US
James N. Higginbotham of Nashville TN US
Supermere Nanoparticles and Methods of Isolation and Use Thereof
This abstract first appeared for US patent application 18695574 titled 'Supermere Nanoparticles and Methods of Isolation and Use Thereof
Original Abstract Submitted
Disclosed herein is a newly identified secreted nanoparticle that is morphologically and molecularly distinct from the recently described nanoparticle termed an exomere. The disclosed nanoparticle is referred to herein as a supermere. Both exomeres and supermeres are amembranous in contrast to membrane-enclosed extracellular vesicles (EVs). Supermeres are smaller and morphologically distinct from exomeres. These supermeres contain cargo with diagnostic and therapeutic applications.