18607390. DEVICES FOR REDUCING CARDIAC VALVE REGURGITATION simplified abstract (EDWARDS LIFESCIENCES CORPORATION)

DEVICES FOR REDUCING CARDIAC VALVE REGURGITATION

Organization Name

EDWARDS LIFESCIENCES CORPORATION

Inventor(s)

Stanton J. Rowe of Newport Coast CA (US)

Robert S. Schwartz of Inver Grove Heights MN (US)

Robert A. Van Tassel of Irvine CA (US)

Vivian Khalil of San Gabriel CA (US)

Erin M. Spinner of Carlsbad CA (US)

Neil S. Zimmerman of Redwood City CA (US)

Alexander J. Siegel of Irvine CA (US)

DEVICES FOR REDUCING CARDIAC VALVE REGURGITATION - A simplified explanation of the abstract

This abstract first appeared for US patent application 18607390 titled 'DEVICES FOR REDUCING CARDIAC VALVE REGURGITATION

The present invention aims to improve the function of a defective heart valve, specifically reducing regurgitation through an atrioventricular heart valve such as the mitral valve or tricuspid valve.

• Device includes an anchor deployed in the tissue of the right ventricle or anchored to the tricuspid valve.
• Flexible anchor rail connects to the anchor and a coaptation element on a catheter rides over the anchor rail.
• Catheter attaches to the proximal end of the coaptation element, with a locking mechanism fixing its position relative to the anchor rail.
• Proximal anchoring feature fixes the proximal end of the coaptation catheter subcutaneously adjacent to the subclavian vein.
• Coaptation element includes an inert covering to reduce regurgitation through contact with the valve leaflets.

Potential Applications: - Treatment of defective heart valves - Reducing regurgitation in patients with atrioventricular heart valve issues - Improving heart function and overall cardiovascular health

Problems Solved: - Addressing regurgitation through defective heart valves - Providing a minimally invasive solution for heart valve repair - Enhancing the effectiveness of tricuspid repair procedures

Benefits: - Improved heart valve function - Reduced regurgitation and associated symptoms - Minimally invasive procedure with potentially faster recovery times

Commercial Applications: Title: Innovative Device for Heart Valve Repair This technology could be used in medical settings for tricuspid repair procedures, potentially improving patient outcomes and reducing the need for more invasive interventions. The market for heart valve repair devices is growing, and this innovation could offer a competitive edge to medical facilities offering advanced cardiovascular care.

Questions about Heart Valve Repair: 1. How does this device compare to traditional methods of heart valve repair? This device offers a minimally invasive approach to tricuspid repair, potentially reducing risks and recovery times compared to traditional open-heart surgeries.

2. What are the long-term implications of using this device for heart valve repair? Long-term studies are needed to fully understand the durability and effectiveness of this device in improving heart valve function over time.

Original Abstract Submitted

The present invention relates to devices and methods for improving the function of a defective heart valve, and particularly for reducing regurgitation through an atrioventricular heart valve (i.e., mitral valve and/or tricuspid valve). For tricuspid repair, the device includes an anchor deployed in the tissue of the right ventricle, in an orifice opening to the right atrium, or anchored to the tricuspid valve. A flexible anchor rail connects to the anchor and a coaptation element on a catheter rides over the anchor rail. The catheter attaches to the proximal end of the coaptation element, and a locking mechanism fixes the position of the coaptation element relative to the anchor rail. There is a proximal anchoring feature to fix the proximal end of the coaptation catheter subcutaneously adjacent the subclavian vein. The coaptation element includes an inert covering and helps reduce regurgitation through contact with the valve leaflets.