COMPOSITION CONTAINING NUCLEIC ACID OLIGOMER

Organization Name

Inventor(s)

COMPOSITION CONTAINING NUCLEIC ACID OLIGOMER - A simplified explanation of the abstract

This abstract first appeared for US patent application 18574655 titled 'COMPOSITION CONTAINING NUCLEIC ACID OLIGOMER

Simplified Explanation

The patent application describes a stable composition containing a nucleic acid oligomer with a phosphorothioate bond, along with a method for producing it efficiently.

The composition includes the nucleic acid oligomer with a specific chemical structure, an alkyl ammonium salt, a nitrile-based organic solvent, water, and an additive with certain compounds.
The invention aims to provide a stable solution for the nucleic acid oligomer, ensuring its integrity and usability in various applications.

Key Features and Innovation

Stable composition of nucleic acid oligomer with phosphorothioate bond.
Efficient production method for the nucleic acid oligomer.
Specific chemical components to maintain stability and usability.

Potential Applications

The technology can be used in various fields such as pharmaceuticals, biotechnology, and research where stable nucleic acid oligomers are required.

Problems Solved

The technology addresses the challenge of maintaining the stability of nucleic acid oligomers with phosphorothioate bonds, which are prone to degradation.

Benefits

Enhanced stability of nucleic acid oligomers.
Improved efficiency in production processes.
Increased usability in different applications.

Commercial Applications

Title: "Stable Nucleic Acid Oligomer Composition for Biomedical Applications"
The technology can be commercialized for pharmaceutical companies, research institutions, and biotech firms requiring stable nucleic acid oligomers for their products and research.

Questions about the Technology

1. How does the stable composition improve the usability of nucleic acid oligomers?

The stable composition ensures the integrity and longevity of the nucleic acid oligomers, making them more reliable for various applications.

2. What are the specific compounds in the additive that contribute to the stability of the composition?

The additive contains compounds selected from a group of specific chemical structures that help maintain the stability of the nucleic acid oligomers.

Original Abstract Submitted

The present invention provides a stable composition containing a nucleic acid oligomer having a phosphorothioate bond, a method for producing the same, and a method for efficiently producing the nucleic acid oligomer from the composition. The composition containing a nucleic acid oligomer having a phosphorothioate bond represented by Formula (1) (wherein symbols are as defined in the specification), an alkyl ammonium salt, a nitrile-based organic solvent, water, and an additive containing at least one compound selected from the group consisting of compounds represented by Formulae (3a) to (3h) is a stable composition.