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18572942. IMPROVED BACILLUS HOST CELL WITH ALTERED REMA/REMB PROTEIN simplified abstract (BASF SE)

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IMPROVED BACILLUS HOST CELL WITH ALTERED REMA/REMB PROTEIN

Organization Name

BASF SE

Inventor(s)

Max Fabian Felle of Ludwigshafen (DE)

Mathis Appelbaum of Ludwigshafen (DE)

Christopher Sauer of Ludwigshafen (DE)

Stefan Janewein of Ludwigshafen (DE)

IMPROVED BACILLUS HOST CELL WITH ALTERED REMA/REMB PROTEIN - A simplified explanation of the abstract

This abstract first appeared for US patent application 18572942 titled 'IMPROVED BACILLUS HOST CELL WITH ALTERED REMA/REMB PROTEIN

The present invention involves a host cell engineered to increase the production of biological compounds, specifically through genetic modifications in the remA and/or remB gene. The method for enhancing the production of polypeptides of interest revolves around cultivating this bacterial host cell.

  • Host cell with genetic modifications in the remA and/or remB gene
  • Increased production of biological compounds
  • Cultivating the bacterial host cell for enhanced production of polypeptides
  • Method for increasing the production of biological compounds
  • Genetic engineering for improved compound production
    • Potential Applications:**

- Biopharmaceutical production - Industrial enzyme production - Biofuel production

    • Problems Solved:**

- Low yields of biological compounds - Inefficient production processes - Costly production methods

    • Benefits:**

- Increased production efficiency - Higher yields of desired compounds - Cost-effective production processes

    • Commercial Applications:**

Title: Enhanced Biological Compound Production Technology This technology can be utilized in various industries such as pharmaceuticals, biotechnology, and bioenergy, offering a competitive edge in the market with increased production capabilities and cost savings.

    • Questions about Enhanced Biological Compound Production Technology:**

1. How does the genetic modification in the remA and remB genes contribute to increased compound production? 2. What are the potential drawbacks or limitations of using this engineered host cell for compound production?


Original Abstract Submitted

The present invention relates to a host cell for increased production of biological compounds. Specifically, the invention relates to a host with genetic modifications in the remA and/or remB gene. The present invention further relates to a method for increased production of at least one polypeptide of interest based on cultivating the bacterial host cell of the present invention.

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