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18566782. ASSAY FOR EXTRINSIC INHIBITION simplified abstract (THE REGENTS OF THE UNIVERSITY OF CALIFORNIA)

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ASSAY FOR EXTRINSIC INHIBITION

Organization Name

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor(s)

Katerina Akassoglou of San Francisco CA (US)

Mark Petersen of San Francisco CA (US)

Anke Meyer-franke of Menlo Park CA (US)

ASSAY FOR EXTRINSIC INHIBITION - A simplified explanation of the abstract

This abstract first appeared for US patent application 18566782 titled 'ASSAY FOR EXTRINSIC INHIBITION

Simplified Explanation: The patent application describes a high-throughput, high-content assay designed to identify a substance that can overcome the inhibition of remyelination caused by an external inhibitor.

Key Features and Innovation:

  • Development of a screening method to find agents that can counteract remyelination inhibition.
  • High-throughput capability for efficient screening of a large number of potential compounds.
  • Focus on high-content analysis to assess the effectiveness of identified agents in promoting remyelination.

Potential Applications: This technology could be applied in drug discovery and development for treating demyelinating diseases such as multiple sclerosis.

Problems Solved: This technology addresses the challenge of identifying compounds that can enhance remyelination in the presence of inhibitory factors.

Benefits:

  • Accelerated discovery of potential therapeutics for demyelinating diseases.
  • Improved understanding of the mechanisms involved in remyelination.

Commercial Applications: Potential commercial uses include pharmaceutical research and development for neurological disorders, as well as potential applications in personalized medicine.

Questions about the Technology: 1. How does this assay differ from traditional screening methods for remyelination-promoting agents? 2. What are the implications of overcoming remyelination inhibition in the treatment of demyelinating diseases?

Frequently Updated Research: Stay informed about the latest advancements in high-throughput screening methods for identifying compounds that promote remyelination in demyelinating diseases.


Original Abstract Submitted

A high-throughput, high-content assay to screen for an agent which overcomes remyelination inhibition by an extrinsic inhibitor.

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