18543320. VERSATILE FLOW THROUGH STRATEGY FOR SELECTIVE SURFACE MODIFICATION simplified abstract (ILLUMINA, INC.)

VERSATILE FLOW THROUGH STRATEGY FOR SELECTIVE SURFACE MODIFICATION

Organization Name

ILLUMINA, INC.

Inventor(s)

Yannan Zhao of Del Mar CA (US)

Florika Macazo of San Diego CA (US)

Rachel Goodridge of San Diego CA (US)

Emily Welch of San Diego CA (US)

Hassan Bohra of Singapore (SG)

Sang Park of San Diego CA (US)

Lisa Savagian of San Diego CA (US)

Borhan Chueh of San Diego CA (US)

Thomas Brubaker of Escondido CA (US)

Shreshtha Mishra of San Diego CA (US)

VERSATILE FLOW THROUGH STRATEGY FOR SELECTIVE SURFACE MODIFICATION - A simplified explanation of the abstract

This abstract first appeared for US patent application 18543320 titled 'VERSATILE FLOW THROUGH STRATEGY FOR SELECTIVE SURFACE MODIFICATION

The method described in the abstract involves modifying an interstitial surface separating recesses by flowing a first fluid over the surface and into the recesses, coating the surface and filling the recesses with the first fluid. The first fluid is then replaced with a second fluid containing a reagent while it remains within the recesses.

• Flow a first fluid over the interstitial surface and into the recesses
• Coat the interstitial surface with the first fluid and fill the recesses with it
• Replace the first fluid with a second fluid containing a reagent
• The method allows for modification of the interstitial surface and recesses efficiently
• The use of different fluids enables specific treatments within the recesses

Potential Applications: - Biomedical research for targeted drug delivery - Microfluidic devices for chemical reactions - Surface modification in manufacturing processes

Problems Solved: - Precise coating and filling of recesses - Controlled delivery of reagents - Enhanced surface treatments

Benefits: - Improved efficiency in modifying surfaces - Targeted and controlled reactions - Versatile applications in various fields

Commercial Applications: Title: Advanced Surface Modification Method for Targeted Treatments This technology can be utilized in pharmaceutical research, microfluidics, and manufacturing processes to enhance precision and control in surface modifications.

Questions about the technology: 1. How does the method ensure precise coating and filling of recesses? 2. What are the advantages of using different fluids for surface modification?

Original Abstract Submitted

A method for modifying an interstitial surface separating recesses from one another can include flowing a first fluid over the interstitial surface and into the recesses, such that the interstitial surface is substantially coated with the first fluid and the recesses are substantially filled with the first fluid; and while the first fluid remains within the recesses, replacing the first fluid coating the interstitial surface with a second fluid comprising a reagent.