18499024. NUCLEIC ACID SEQUENCING USING NANOPORES (Western Digital Technologies, Inc.)
NUCLEIC ACID SEQUENCING USING NANOPORES
Organization Name
Western Digital Technologies, Inc.
Inventor(s)
Justin P. Kinney of San Jose CA US
Daniel Bedau of San Jose CA US
NUCLEIC ACID SEQUENCING USING NANOPORES
This abstract first appeared for US patent application 18499024 titled 'NUCLEIC ACID SEQUENCING USING NANOPORES
Original Abstract Submitted
Disclosed herein are devices, systems, and methods for sequencing nucleic acids using a nanopore. A nucleic acid molecule is fragmented into smaller portions (e.g., individual nucleotides), which are then routed through a nanopore for detection. A device for single-nucleotide sequencing may include a fluidic channel, a disintegrator configured to cleave off portions of a nucleic acid in the fluidic channel, a nanopore coupled to the fluidic channel, and first and second electrodes situated to apply an electrostatic force on the portions of the nucleic acid to divert them out of the fluidic channel and through the nanopore.