Wisconsin Alumni Research Foundation patent applications published on July 11th, 2024

Summary of the patent applications from Wisconsin Alumni Research Foundation on July 11th, 2024

1. **Summary**: The recent patents filed by this organization focus on innovative technologies in various fields. One patent involves the growth of complex metal oxide films using hybrid pulsed laser deposition, combining molecular beam epitaxy and pulsed laser deposition techniques. Another patent discusses genetically modified influenza gene products for inhibiting virus replication and serving as vaccine backbones. Additionally, there is a patent on photoreceptor scaffolds for transplantation, aiming to improve cell survival, integration, and visual function.

2. **Key Points of Patents**:

  * Hybrid Pulsed Laser Deposition:
    - Combines MBE and PLD techniques.
    - Enables growth of complex metal oxide films with high stoichiometries.
    - Layered structure enhances film properties.
  * Genetically Modified Influenza Gene Products:
    - DIPs inhibit wild-type virus replication.
    - Can be used for treatment, immunostimulatory purposes, and as vaccine backbones.
  * Photoreceptor Scaffolds:
    - Includes a cell support layer with honeycomb-shaped reservoirs.
    - Fluidly connected through-holes for cell delivery.
    - May include retinal pigment epithelial cells for enhanced outcomes.

3. **Notable Applications**:

  * Hybrid Pulsed Laser Deposition:
    - Semiconductor industry for advanced electronic devices.
    - Energy storage systems for improved performance.
    - Catalysis for chemical reactions.
  * Genetically Modified Influenza Gene Products:
    - Treatment for influenza infection.
    - Immunostimulatory agent for boosting immune response.
    - Attenuated vaccine backbone for vaccination purposes.
  * Photoreceptor Scaffolds:
    - Retinal regeneration therapies.
    - Treatment of retinal degenerative diseases.
    - Vision restoration procedures.

Patent applications for Wisconsin Alumni Research Foundation on July 11th, 2024

COMPUTER VISION-BASED FEEDING MONITORING AND METHOD THEREFOR (18615874)

Main Inventor

Joao Reboucas Dorea

SYSTEMS AND METHODS FOR CONTROLLING SCATTER IN COMPUTED TOMOGRAPHY DATA (17971617)

Main Inventor

Guang-Hong Chen

SENOLYTIC CRISPR CAR T CELLS PRODUCED BY CRISPR-CAS9 GENOME EDITING (18295036)

Main Inventor

Krishanu Saha

Introducer Needle and Stylet for Interventional Procedures (18487228)

Main Inventor

Annie M. Zlevor

SELF-ASSEMBLING ROD-COIL COPOLYMERS FOR CARBON NANOTUBE SORTING AND THE FABRICATION OF CARBON NANOTUBE FILMS (18152900)

Main Inventor

Padma Gopalan

MECHANICALLY STABLE AND HIGH CELL DENSITY HONEYCOMB RETINAL SCAFFOLD DESIGN FOR TRANSPLANTATION THERAPY OF PHOTORECEPTOR CELLS AND RETINAL PIGMENT EPITHELIUM (17769549)

Main Inventor

Zhenqiang Ma

GENETICALLY MODIFIED GENES AND CELLS, AND METHODS OF USING SAME FOR SILENCING VIRUS GENE EXPRESSION (18373569)

Main Inventor

Nathan Mark SHERER

CRYPTIC PROTEINS EXPRESSED FROM DEFECTIVE VIRAL GENOMES INTERFERE WITH INFLUENZA VIRUS REPLICATION (18495338)

Main Inventor

Andrew Mehle

HYBRID PULSED LASER DEPOSITION OF COMPLEX OXIDE THIN FILMS MADE FROM ELEMENTS HAVING A LARGE VAPOR PRESSURE MISMATCH (18151550)

Main Inventor

Chang-Beom Eom