Unknown Organization (20240402192). KIT FOR QUIESCENT DETECTING ALPHA-SYNUCLEIN AGGREGATES

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KIT FOR QUIESCENT DETECTING ALPHA-SYNUCLEIN AGGREGATES

Organization Name

Unknown Organization

Inventor(s)

Hengxu Mao of Guangzhou (CN)

Pingyi Xu of Guangzhou (CN)

Yaoyun Kuang of Guangzhou (CN)

Xinling Yang of Urumqi (CN)

Lin Lu of Guangzhou (CN)

Wenyuan Guo of Guangzhou (CN)

Hongyan Li of Urumqi (CN)

Yuxuan Yong of Urumqi (CN)

Wenjun Wu of Zhongshan (CN)

Xiaoyun Huang of Dongguan (CN)

KIT FOR QUIESCENT DETECTING ALPHA-SYNUCLEIN AGGREGATES

This abstract first appeared for US patent application 20240402192 titled 'KIT FOR QUIESCENT DETECTING ALPHA-SYNUCLEIN AGGREGATES



Original Abstract Submitted

a kit for quiescent detecting alpha-synuclein aggregates is provided by the present application, relating to the field of biotechnology. the kit includes recombinant monomeric alpha-synuclein, ammonium sulfate and thioflavine t. the incubation conditions are modified in this application, allowing the detection of pre-formed fibrils diluted to 10 picogram per milliliter for the first time, with 1 microliter of sample translating to a total of 10 fg of pre-formed fibrils detected, with a sensitivity of fg level in a single cycle.