US Patent Application 18322675. SYSTEMS, METHODS, AND COMPOSITIONS FOR RNA-GUIDED RNA-TARGETING CRISPR EFFECTORS simplified abstract
SYSTEMS, METHODS, AND COMPOSITIONS FOR RNA-GUIDED RNA-TARGETING CRISPR EFFECTORS
Organization Name
Massachusetts Institute of Technology
Inventor(s)
Omar Osama Abudayyeh of Cambridge MA (US)
Jonathan S. Gootenberg of Cambridge MA (US)
Wenyuan Zhou of Cambridge MA (US)
Hiroshi Nishimasu of Tokyo (JP)
Cian Franz Schmitt-ulms of Cambridge MA (US)
SYSTEMS, METHODS, AND COMPOSITIONS FOR RNA-GUIDED RNA-TARGETING CRISPR EFFECTORS - A simplified explanation of the abstract
This abstract first appeared for US patent application 18322675 titled 'SYSTEMS, METHODS, AND COMPOSITIONS FOR RNA-GUIDED RNA-TARGETING CRISPR EFFECTORS
Simplified Explanation
- This patent application is about systems, methods, and compositions for using RNA-guided RNA-targeting CRISPR effectors for treating diseases and as diagnostics. - The application also discloses the use of nucleotide deaminase functionalized CRISPR systems for various purposes such as RNA editing, RNA knockdown, viral resistance, splicing modulation, RNA tracking, translation modulation, and epi-transcriptomic modifications.
Original Abstract Submitted
This disclosure provides systems, methods, and compositions for RNA-guided RNA-targeting CRISPR effectors for the treatment of diseases, and for use as diagnostics. In addition, nucleotide deaminase functionalized CRISPR systems for RNA editing RNA knockdown, viral resistance, splicing modulation, RNA tracking, translation modulation, and epi-transcriptomic modifications are disclosed.
