Tangshan People's Hospital (20240230653). USE OF BAZ1B K426hy AND POLYCLONAL ANTIBODY THEREOF IN PREPARATION OF PRODUCT FOR TUMOR DETECTION simplified abstract

USE OF BAZ1B_K426hy AND POLYCLONAL ANTIBODY THEREOF IN PREPARATION OF PRODUCT FOR TUMOR DETECTION

Organization Name

Tangshan People's Hospital

Inventor(s)

Jingwu Li of Tangshan (CN)

Yufeng Li of Tangshan (CN)

Shuqing Wang of Tangshan (CN)

Jinghua Zhang of Tangshan (CN)

Jinghua Wu of Tangshan (CN)

Fen Hu of Tangshan (CN)

Yuan Yu of Tangshan (CN)

Yan Liu of Tangshan (CN)

Yuhui Li of Tangshan (CN)

Xuan Zheng of Tangshan (CN)

USE OF BAZ1B_K426hy AND POLYCLONAL ANTIBODY THEREOF IN PREPARATION OF PRODUCT FOR TUMOR DETECTION - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240230653 titled 'USE OF BAZ1B_K426hy AND POLYCLONAL ANTIBODY THEREOF IN PREPARATION OF PRODUCT FOR TUMOR DETECTION

The present disclosure involves the use of baz1b_k426hy in developing a product for tumor detection in the field of biotechnology. It also includes a group of immunogenic polypeptides, such as polypeptide a and polypeptide b. An anti-baz1b_k426hy polyclonal antibody is created through mixed immunization of an animal with the immunogenic polypeptide. This polyclonal antibody can specifically identify the endogenous protein baz1b_k426hy through various assays like ELISA, dot blot, and Western blot, which are useful for tumor and Williams syndrome detection.

• Use of baz1b_k426hy in tumor detection product preparation
• Creation of immunogenic polypeptides, including polypeptide a and polypeptide b
• Development of anti-baz1b_k426hy polyclonal antibody through mixed immunization
• Specific recognition of endogenous protein baz1b_k426hy for tumor and Williams syndrome detection
• Utilization of various assays like ELISA, dot blot, and Western blot for detection

Potential Applications: - Tumor detection products - Williams syndrome detection tools - Biotechnological research and development

Problems Solved: - Improved specificity in tumor detection - Enhanced detection capabilities for Williams syndrome - Advancement in biotechnological applications

Benefits: - Early and accurate tumor detection - Precise identification of Williams syndrome - Potential for further research and development in biotechnology

Commercial Applications: Title: "Innovative Tumor Detection Products Using baz1b_k426hy" This technology can be utilized in the development of diagnostic tools for tumor detection, catering to the medical industry's needs. It has the potential to revolutionize the way tumors are detected and diagnosed, leading to better patient outcomes and improved healthcare practices.

Questions about the technology: 1. How does the use of baz1b_k426hy improve tumor detection compared to existing methods? 2. What are the potential implications of utilizing the anti-baz1b_k426hy polyclonal antibody in Williams syndrome detection?

Original Abstract Submitted

the present disclosure provides the use of baz1b_k426hy in the preparation of a product for tumor detection and belongs to the field of biotechnology. the present disclosure further provides a group of immunogenic polypeptides, including polypeptide a and polypeptide b. an anti-baz1b_k426hy polyclonal antibody is prepared by conducting mixed immunization on an animal with the immunogenic polypeptide. the polyclonal antibody can specifically recognize an endogenous protein baz1b_k426hy by enzyme-linked immunosorbent assay (elisa)/dot blot/western blot, which is used for preparation of detection products for tumors and williams syndrome.