Robert bosch gmbh (20240189821). Method and Device for Trapping at Least One Nucleated Cell Using at Least One Electrode for a Microfluidic Device simplified abstract

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Method and Device for Trapping at Least One Nucleated Cell Using at Least One Electrode for a Microfluidic Device

Organization Name

robert bosch gmbh

Inventor(s)

Thomas Buck of Tamm (DE)

Samir Kadic of Langenau (DE)

Franz Laermer of Weil Der Stadt (DE)

Michael Dreschmann of Muenchen (DE)

Jochen Hoffmann of Renningen (DE)

Anne Serout of Aidlingen (DE)

Method and Device for Trapping at Least One Nucleated Cell Using at Least One Electrode for a Microfluidic Device - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240189821 titled 'Method and Device for Trapping at Least One Nucleated Cell Using at Least One Electrode for a Microfluidic Device

The abstract describes a method for trapping nucleated cells using electrodes in a microfluidic device. The method involves applying a sample liquid containing nucleated cells to a carrier substrate and generating an electric field to trap the cells in a microcavity.

  • The method utilizes electrodes to trap nucleated cells in a microfluidic device.
  • An application signal is used to apply the sample liquid to a carrier substrate.
  • A current signal is provided to the electrodes to generate an electric field in a microcavity.
  • The electric field traps nucleated cells as target cells in the microcavity.

Potential Applications: - Cell sorting and analysis in biological research. - Medical diagnostics for identifying specific cell types. - Drug development and screening processes.

Problems Solved: - Efficient trapping and isolation of nucleated cells. - Precise control over cell manipulation in microfluidic systems.

Benefits: - Enhanced accuracy and sensitivity in cell analysis. - Automation of cell trapping processes. - Reduction in sample contamination.

Commercial Applications: Title: "Advanced Cell Trapping Technology for Biomedical Research" This technology can be applied in research laboratories, medical diagnostics companies, and pharmaceutical companies for various cell-related applications.

Prior Art: Prior research may include studies on microfluidic devices for cell manipulation and trapping, as well as electrode-based cell sorting techniques.

Frequently Updated Research: Ongoing studies may focus on optimizing the trapping efficiency of nucleated cells in microfluidic devices and exploring new applications for this technology.

Questions about the Technology: 1. How does this method compare to traditional cell trapping techniques? 2. What are the potential limitations of using electrodes for cell trapping in microfluidic devices?


Original Abstract Submitted

a method for trapping at least one nucleated cell using at least one electrode for a microfluidic device is disclosed. the method includes (i) outputting an application signal that causes a sample liquid comprising the at least one nucleated cell to be applied to a carrier substrate of the microfluidic device, and (ii) providing a current signal to an interface with the at least one electrode in order to generate, at or in a microcavity of the carrier substrate, an electric field configured to trap the at least one nucleated cell as a target cell in the microcavity.