PROMEGA CORPORATION (20240302339). OXYGEN CONSUMPTION ASSAY simplified abstract

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OXYGEN CONSUMPTION ASSAY

Organization Name

PROMEGA CORPORATION

Inventor(s)

Ian Marozas of Madison WI (US)

Zhiyang Zeng of Madison WI (US)

Wenhui Zhou of Madison WI (US)

Mike Valley of Madison WI (US)

Jolanta Vidugiriene of Madison WI (US)

James Cali of Madison WI (US)

Tony Lauer of Madison WI (US)

OXYGEN CONSUMPTION ASSAY - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240302339 titled 'OXYGEN CONSUMPTION ASSAY

    • Simplified Explanation:**

The patent application describes assays using oxygen-sensitive fluorescent materials to detect oxygen levels, specifically in living cells.

    • Key Features and Innovation:**

- Utilizes oxygen-sensitive fluorescent particles for monitoring oxygen consumption rate and metabolic fitness of living cells - Provides a non-invasive method for assessing cellular oxygen levels - Enables real-time monitoring of cellular oxygen dynamics

    • Potential Applications:**

- Biomedical research for studying cellular metabolism and oxygen consumption - Drug development to assess the effects of compounds on cellular oxygen levels - Environmental monitoring to track oxygen levels in aquatic ecosystems

    • Problems Solved:**

- Enables accurate and sensitive measurement of oxygen levels in living cells - Provides a convenient and efficient method for assessing cellular metabolic activity - Offers a non-destructive way to monitor oxygen consumption in real-time

    • Benefits:**

- Facilitates a deeper understanding of cellular metabolism and oxygen utilization - Allows for the evaluation of cellular health and metabolic function - Enhances research capabilities in various fields such as biology, medicine, and environmental science

    • Commercial Applications:**

Title: Oxygen-Sensitive Fluorescent Materials for Cellular Metabolism Monitoring Description: This technology can be applied in pharmaceutical research, biotechnology, and environmental monitoring industries to improve cellular analysis and metabolic studies.

    • Questions about Oxygen-Sensitive Fluorescent Materials:**

1. How do oxygen-sensitive fluorescent materials work in detecting oxygen levels in living cells? 2. What are the advantages of using fluorescent particles for monitoring cellular oxygen consumption?


Original Abstract Submitted

provided herein are assays utilizing oxygen-sensitive fluorescent materials for the detection of oxygen. in particular, oxygen-sensitive fluorescent particles are provided for monitoring the oxygen consumption rate and metabolic fitness of living cells.