LIGHT BIO, INC. (20240279621). NOVEL LUCIFERASES AND METHODS FOR USING SAME simplified abstract
Contents
NOVEL LUCIFERASES AND METHODS FOR USING SAME
Organization Name
Inventor(s)
Il'ya Viktorovich Yampol'skiy of Moscow (RU)
NOVEL LUCIFERASES AND METHODS FOR USING SAME - A simplified explanation of the abstract
This abstract first appeared for US patent application 20240279621 titled 'NOVEL LUCIFERASES AND METHODS FOR USING SAME
The present invention involves novel luciferases encoded by nucleic acid molecules isolated from fungi or obtained through genetic engineering methods. Proteins encoded by these nucleic acids, as well as functional fragments, homologs, and mutants, are also included in the invention. Antibodies specific to these proteins are provided, along with host cells, stable cell lines, and transgenic organisms containing the nucleic acid molecules.
- Nucleic acid molecules encoding novel luciferases
- Proteins encoded by the nucleic acids
- Antibodies specific to the proteins
- Host cells, stable cell lines, and transgenic organisms containing the nucleic acid molecules
- Applications in labeling organisms, cells, cellular organelles, and proteins
- Methods for detecting protein-protein interactions and testing promoter activity
- Kits for using the proteins and nucleic acids in various methods and applications
Potential Applications: - Biotechnology research - Medical diagnostics - Pharmaceutical development - Environmental monitoring - Forensic science
Problems Solved: - Lack of efficient labeling methods - Limited tools for studying protein interactions - Challenges in testing promoter activity
Benefits: - Enhanced research capabilities - Improved understanding of biological processes - Increased accuracy in diagnostic testing - Potential for new drug discoveries
Commercial Applications: Title: Novel Luciferases for Biotechnology Applications This technology has the potential to revolutionize biotechnology research, medical diagnostics, pharmaceutical development, environmental monitoring, and forensic science. The use of novel luciferases and their encoding nucleic acid molecules opens up new possibilities for labeling, studying protein interactions, and testing promoter activity in various applications.
Questions about Novel Luciferases: 1. How do novel luciferases differ from traditional luciferases in terms of efficiency and specificity? 2. What are the potential limitations or challenges in using these novel luciferases for practical applications?
Original Abstract Submitted
the present invention is directed to nucleic acid molecules which encode novel luciferases, functional fragments thereof, homologs and mutants, as well as to proteins encoded by said nucleic acids. the nucleic acid molecules of interest are isolated from fungi or obtained by genetic engineering methods. also, host cells, stable cell lines and transgenic organisms comprising said nucleic acid molecules are provided. in addition, antibodies specific to the proteins of the present invention are provided. said proteins and nucleic acids are used in many applications and methods, in particular, in labelling organisms, cells, cellular organelles, or proteins. also, said protein and nucleotide compositions are used in methods for detecting protein-protein interactions, for testing promoter activity under various conditions. finally, provided are kits for the use of proteins and nucleic acids of the present invention in the diversity of methods and applications.
