INBIOSE N.V. (20240327888). LACTO-N-BIOSE CONVERTING FUCOSYLTRANSFERASES simplified abstract

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LACTO-N-BIOSE CONVERTING FUCOSYLTRANSFERASES

Organization Name

INBIOSE N.V.

Inventor(s)

Sofie Aesaert of Zwijnaarde (BE)

Joeri Beauprez of Zwijnaarde (BE)

Gert Peters of Zwijnaarde (BE)

Kristof Vandewalle of Zwijnaarde (BE)

Annelies Vercauteren of Zwijnaarde (BE)

LACTO-N-BIOSE CONVERTING FUCOSYLTRANSFERASES - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240327888 titled 'LACTO-N-BIOSE CONVERTING FUCOSYLTRANSFERASES

Simplified Explanation

The patent application is about a method for producing a compound using metabolically engineered cells in a cultivation process, such as fermentation.

  • Metabolically engineered cells are used to express an alpha-1,2-fucosyltransferase that acts on a specific galactose residue.
  • The method allows for the purification of the compound produced from the cultivation process.

Key Features and Innovation

  • Use of metabolically engineered cells expressing alpha-1,2-fucosyltransferase.
  • Production of a compound through fermentation.
  • Purification of the compound from the cultivation process.

Potential Applications

The technology can be applied in various industries such as pharmaceuticals, biotechnology, and food production for the efficient production of specific compounds.

Problems Solved

  • Enables the production of compounds using metabolically engineered cells.
  • Provides a method for purifying the compound from the cultivation process.

Benefits

  • Increased efficiency in compound production.
  • Cost-effective method for obtaining purified compounds.

Commercial Applications

The technology can be utilized in pharmaceutical companies for drug production, biotech firms for specialty chemical manufacturing, and food companies for the production of functional ingredients.

Questions about the Technology

What are the potential industrial applications of this technology?

The technology can be applied in pharmaceuticals, biotechnology, and food production for the efficient production of specific compounds.

How does the use of metabolically engineered cells improve compound production?

Metabolically engineered cells expressing alpha-1,2-fucosyltransferase enable the efficient production of compounds through fermentation processes.


Original Abstract Submitted

the present invention is in the technical field of synthetic biology and metabolic engineering. more particularly, the present invention is in the technical field of metabolically engineered cells and use of said cells in a cultivation, preferably a fermentation. the present invention describes a cell and a method for production of a compound. the cell expresses an alpha-1,2-fucosyltransferase that has galactoside alpha-1,2-fucosyltransferase activity on the galactose residue of gal-b1,3-glcnac (lnb, lacto-n-biose). furthermore, the present invention provides for purification of said compound from the cultivation.