INBIOSE N.V. (20240294959). CELLULAR PRODUCTION OF BIOPRODUCTS simplified abstract
Contents
- 1 CELLULAR PRODUCTION OF BIOPRODUCTS
- 1.1 Organization Name
- 1.2 Inventor(s)
- 1.3 CELLULAR PRODUCTION OF BIOPRODUCTS - A simplified explanation of the abstract
- 1.4 Simplified Explanation
- 1.5 Key Features and Innovation
- 1.6 Potential Applications
- 1.7 Problems Solved
- 1.8 Benefits
- 1.9 Commercial Applications
- 1.10 Prior Art
- 1.11 Frequently Updated Research
- 1.12 Questions about Metabolically Engineered Cells for Neu(N)Ac-Containing Compound Production
- 1.13 Original Abstract Submitted
CELLULAR PRODUCTION OF BIOPRODUCTS
Organization Name
Inventor(s)
Joeri Beauprez of Zwijnaarde (BE)
Pieter Coussement of Zwijnaarde (BE)
Thomas Decoene of Zwijnaarde (BE)
Annelies Vercauteren of Zwijnaarde (BE)
CELLULAR PRODUCTION OF BIOPRODUCTS - A simplified explanation of the abstract
This abstract first appeared for US patent application 20240294959 titled 'CELLULAR PRODUCTION OF BIOPRODUCTS
Simplified Explanation
The patent application pertains to the field of synthetic biology and metabolic engineering, specifically focusing on metabolically engineered cells used in cultivation, preferably fermentation, to produce a bioproduct, such as an N-acetylneuraminic acid (Neu(N)Ac)-containing compound.
- Metabolically engineered cells are utilized in cultivation, particularly fermentation, to produce Neu(N)Ac-containing compounds.
- The cells are modified to express or alter the activity of at least one Neunac synthase for the production of the desired compound.
- The invention also includes a method for purifying the Neu(N)Ac-containing compound from the cultivation.
Key Features and Innovation
- Metabolically engineered cells for producing Neu(N)Ac-containing compounds.
- Modification of Neunac synthase expression or activity in cells.
- Purification method for the produced compound.
Potential Applications
The technology can be applied in:
- Pharmaceutical industry for drug development.
- Food industry for functional food production.
- Biotechnology for research purposes.
Problems Solved
- Efficient production of Neu(N)Ac-containing compounds.
- Enhanced control over the synthesis process.
- Simplified purification methods.
Benefits
- Increased production yields.
- Cost-effective manufacturing process.
- Diversification of product offerings.
Commercial Applications
- SEO-optimized title: Applications of Metabolically Engineered Cells for Neu(N)Ac-Containing Compound Production
The technology can be commercially utilized in:
- Pharmaceutical companies for drug synthesis.
- Food manufacturers for adding functional ingredients.
- Biotech firms for research and development.
Prior Art
Readers can explore prior research on:
- Metabolic engineering in bioproduction.
- Synthesis of Neu(N)Ac-containing compounds.
Frequently Updated Research
Stay updated on:
- Advances in metabolic engineering techniques.
- Novel applications of Neu(N)Ac-containing compounds.
Questions about Metabolically Engineered Cells for Neu(N)Ac-Containing Compound Production
What are the potential challenges in scaling up the production of Neu(N)Ac-containing compounds using metabolically engineered cells?
Scaling up production may face challenges such as maintaining cell viability, optimizing fermentation conditions, and ensuring consistent product quality.
How does the modification of Neunac synthase expression impact the yield and purity of the produced Neu(N)Ac-containing compound?
Modifying Neunac synthase expression can enhance the yield and purity of the compound by regulating the enzymatic pathway involved in its synthesis.
Original Abstract Submitted
the present invention is in the technical field of synthetic biology and metabolic engineering. more particularly, the present invention is in the technical field of metabolically engineered cells and use of said cells in a cultivation, preferably fermentation. the present invention describes a metabolically engineered cell and a method by cultivation, preferably fermentation, with said cell for production of a bioproduct. more specifically, the present invention describes a metabolically engineered cell and a method by cultivation, preferably fermentation, with said cell for production of an n-acetylneuraminic acid (neu(n)ac)-containing compound, wherein (n) is 4, 5, 7, 8 or 9 or a combination thereof. the metabolically engineered cell comprises a pathway for production of said neu(n)ac-containing compound and is modified in the expression or activity of at least one neunac synthase according to the present invention. furthermore, the present invention provides for purification of said neu(n)ac-containing compound from the cultivation.
