ILLUMINA, INC. patent applications published on June 27th, 2024
Summary of the patent applications from ILLUMINA, INC. on June 27th, 2024
1. Summary: The recent patents filed by Illumina, Inc. focus on innovative technologies in DNA sequencing and microfabrication. The first patent involves context-dependent base calling using k-mer-specific centroids to enhance sequencing accuracy. The second patent describes a method for precise functionalization of microscale features using positive photoresist. The third patent introduces electromechanical sequence detectors for efficient entity detection in various applications.
2. Key Points of Patents: - Patent 1: Context-dependent base calling with k-mer-specific centroids for improved sequencing accuracy. - Memory stores k-mer-specific centroids for k-mers. - Centroids are learned through training a base calling pipeline. - Predicted centroids are generated by transforming time series data. - Training loss is determined by comparing predicted intensity values with known values. - Updated centroids are used at runtime for base calling based on k-mer context.
- Patent 2: Method for precise functionalization of microscale features using positive photoresist. - Positive photoresist deposited over substrate with depressions. - Exposed to UV light at non-perpendicular, non-parallel angle. - Soluble and insoluble portions of photoresist in each depression. - Functionalized layers selectively deposited over substrate portions.
- Patent 3: Electromechanical sequence detectors for efficient entity detection. - System includes mechanical-change sensor, shape-to-signal transduction component, analysis subsystem, and control subsystem. - Enables real-time monitoring and adjustment of operational parameters.
3. Notable Applications: - DNA sequencing and genomics research for enhanced accuracy and efficiency. - Microelectronics manufacturing, microfluidics, and biomedical devices for precise functionalization. - Security systems, industrial automation, robotics, medical devices, and environmental monitoring for efficient entity detection.
Contents
- 1 Patent applications for ILLUMINA, INC. on June 27th, 2024
- 1.1 FLOW CELLS (18542470)
- 1.2 FLOW CELLS (18542511)
- 1.3 FLOW CELLS (18542447)
- 1.4 VERSATILE FLOW THROUGH STRATEGY FOR SELECTIVE SURFACE MODIFICATION (18543320)
- 1.5 METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES (18393220)
- 1.6 ARRAYS INCLUDING A RESIN FILM AND A PATTERNED POLYMER LAYER (18590738)
- 1.7 Systems and Methods for Capture and Enrichment of Clustered Beads on Flow Cell Substrates (18539988)
- 1.8 MONOCLONAL CLUSTERING USING DOUBLE STRANDED DNA SIZE EXCLUSION WITH PATTERNED SEEDING (18531285)
- 1.9 TUNING AND CALIBRATION FEATURES OF A SEQUENCE-DETECTION SYSTEM (18601045)
- 1.10 MULTI-SURFACE BIOLOGICAL SAMPLE IMAGING SYSTEM AND METHOD (18389877)
- 1.11 METHODS FOR MAKING FLOW CELLS (18520093)
- 1.12 CONTEXT-DEPENDENT BASE CALLING (18391487)
Patent applications for ILLUMINA, INC. on June 27th, 2024
FLOW CELLS (18542470)
Main Inventor
Johan Sebastian Basuki
FLOW CELLS (18542511)
Main Inventor
Gianluca Andrea Artioli
FLOW CELLS (18542447)
Main Inventor
Johan Sebastian Basuki
VERSATILE FLOW THROUGH STRATEGY FOR SELECTIVE SURFACE MODIFICATION (18543320)
Main Inventor
Yannan Zhao
METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES (18393220)
Main Inventor
Antoine Francais
ARRAYS INCLUDING A RESIN FILM AND A PATTERNED POLYMER LAYER (18590738)
Main Inventor
Wayne N. George
Systems and Methods for Capture and Enrichment of Clustered Beads on Flow Cell Substrates (18539988)
Main Inventor
Naneki McCallum
MONOCLONAL CLUSTERING USING DOUBLE STRANDED DNA SIZE EXCLUSION WITH PATTERNED SEEDING (18531285)
Main Inventor
Aathavan Karunakaran
TUNING AND CALIBRATION FEATURES OF A SEQUENCE-DETECTION SYSTEM (18601045)
Main Inventor
Jeffrey G. Mandell
MULTI-SURFACE BIOLOGICAL SAMPLE IMAGING SYSTEM AND METHOD (18389877)
Main Inventor
Shaoping LU
METHODS FOR MAKING FLOW CELLS (18520093)
Main Inventor
Jeffrey S. Fisher
CONTEXT-DEPENDENT BASE CALLING (18391487)
Main Inventor
Gery Vessere
