IFOM - FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE (20250066784). THERAPEUTIC OLIGONUCLEOTIDES

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THERAPEUTIC OLIGONUCLEOTIDES

Organization Name

IFOM - FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE

Inventor(s)

Fabrizio D'adda Di Fagagna of Milano (IT)

Francesca Rossiello of Milano (IT)

Julio Aguado of Milano (IT)

Corey Jones-weinert of Milano (IT)

THERAPEUTIC OLIGONUCLEOTIDES

This abstract first appeared for US patent application 20250066784 titled 'THERAPEUTIC OLIGONUCLEOTIDES

Original Abstract Submitted

the present invention relates to an oligonucleotide comprising one of the following sequence: (ttaggg) seq id no. 1. (tagggt) seq id no. 2, (agggtt) seq id no. 3, (gggtta) seq id no. 4, (ggttag) seq id no. 5 or (gttagg) seq id no. 6 or a complementary sequence thereof or a fragment or a variant or a mixture thereof for use in the treatment and/or prevention of a disease characterized by alternative lengthening of telomeres or a non-cancer condition associated with telomere dysfunction and relative pharmaceutical compositions and to relative pharmaceutical composition and method.