Dermatology Hospital, Southern Medical University (20240262871). FUSION PROTEIN FOR DETECTING NEUROSYPHILIS AND KIT THEREOF simplified abstract
Contents
FUSION PROTEIN FOR DETECTING NEUROSYPHILIS AND KIT THEREOF
Organization Name
Dermatology Hospital, Southern Medical University
Inventor(s)
Xiaohui Zhang of Guangzhou (CN)
Liuyuan Wang of Guangzhou (CN)
Xinying Leng of Guangzhou (CN)
FUSION PROTEIN FOR DETECTING NEUROSYPHILIS AND KIT THEREOF - A simplified explanation of the abstract
This abstract first appeared for US patent application 20240262871 titled 'FUSION PROTEIN FOR DETECTING NEUROSYPHILIS AND KIT THEREOF
The disclosure provides a fusion protein for detecting neurosyphilis and a kit for the same purpose. It introduces a novel method of diagnosing neurosyphilis by detecting the Nichols Houston strain TP0136 antibody level.
- Using molecular biology gene cloning and expression technologies, a recombinant protein of the syphilis Nichols Houston strain TP0136 is produced.
- A luciferase immunoprecipitation method is established for detecting the Nichols Houston strain TP0136 antibody.
- A kit is assembled with high sensitivity and prediction accuracy, large detection throughput, simple operation, and easy popularization.
- Potential Applications:**
This technology can be used in medical diagnostics and research laboratories for the accurate detection of neurosyphilis.
- Problems Solved:**
This technology addresses the need for a more effective and reliable method of diagnosing neurosyphilis.
- Benefits:**
The fusion protein and kit offer high sensitivity, prediction accuracy, and ease of use, making them valuable tools in the diagnosis of neurosyphilis.
- Commercial Applications:**
"Neurosyphilis Detection Fusion Protein Kit" - This technology can be commercialized as a diagnostic kit for healthcare facilities and research institutions.
- Prior Art:**
Prior research on neurosyphilis diagnosis and detection methods can be found in medical journals and scientific databases.
- Frequently Updated Research:**
Stay updated on advancements in molecular biology techniques and diagnostic tools for neurosyphilis detection.
- Questions about Neurosyphilis Detection Fusion Protein:**
1. What are the potential implications of using this fusion protein in clinical settings? 2. How does this technology compare to existing methods of neurosyphilis diagnosis?
Original Abstract Submitted
a fusion protein for detecting neurosyphilis and a kit thereof are provided in this disclosure. it is unexpectedly found in this disclosure that detecting the nichols houston strain tp0136 antibody level for diagnosis of neurosyphilis makes up a blank of diagnosis and detection methods of the neurosyphilis. using molecular biology gene cloning and expression technologies, a syphilis nichols houston strain tp0136 recombinant protein is obtained, a luciferase immunoprecipitation method for detecting a nichols houston strain tp0136 antibody is established, and a kit is assembled. such a kit has such unexpected technical effects of high sensitivity and high prediction accuracy, and has advantages of large detection throughput, simple operation and easy popularization.
