Canon kabushiki kaisha (20240118207). METHOD FOR DETECTING AND MEASURING TARGET SUBSTANCE ON BASIS OF MEASUREMENT OF POLARIZATION ANISOTROPY, AND PARTICLES USED THEREFOR simplified abstract

METHOD FOR DETECTING AND MEASURING TARGET SUBSTANCE ON BASIS OF MEASUREMENT OF POLARIZATION ANISOTROPY, AND PARTICLES USED THEREFOR

Organization Name

canon kabushiki kaisha

Inventor(s)

NORISHIGE Kakegawa of Tokyo (JP)

TAKAHIRO Masumura of Tochigi (JP)

TEIGO Sakakibara of Tokyo (JP)

IKUO Nakajima of Tokyo (JP)

FUMIO Yamauchi of Kanagawa (JP)

KENGO Kanazaki of Kanagawa (JP)

METHOD FOR DETECTING AND MEASURING TARGET SUBSTANCE ON BASIS OF MEASUREMENT OF POLARIZATION ANISOTROPY, AND PARTICLES USED THEREFOR - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240118207 titled 'METHOD FOR DETECTING AND MEASURING TARGET SUBSTANCE ON BASIS OF MEASUREMENT OF POLARIZATION ANISOTROPY, AND PARTICLES USED THEREFOR

Simplified Explanation

The method described in the patent application involves using two different particles that specifically bind to a target substance in a sample liquid, and then determining the presence or absence, as well as the concentration, of the target substance based on the polarization anisotropy of the mixed liquid containing the particles.

• Rare earth complex-containing first particle specifically binds to target substance
• Second particle with larger diameter also binds to target substance
• Mixing sample liquid with particles to create mixed liquid
• Determining presence/absence and concentration of target substance based on polarization anisotropy

Potential Applications

This technology could be applied in various fields such as medical diagnostics, environmental monitoring, food safety testing, and pharmaceutical research.

Problems Solved

This method provides high detection sensitivity for measuring target substances in sample liquids, allowing for accurate and efficient analysis.

Benefits

- High detection sensitivity - Accurate measurement of target substances - Efficient analysis process

Potential Commercial Applications

- Medical diagnostic devices - Environmental monitoring equipment - Food safety testing kits - Pharmaceutical research tools

Possible Prior Art

One possible prior art could be the use of fluorescent particles for detecting target substances in sample liquids. However, the specific combination of rare earth complex-containing particles and larger diameter particles for polarization anisotropy measurement may be a novel aspect of this technology.

How does this method compare to traditional detection methods for target substances in sample liquids?

This article does not provide a direct comparison between this method and traditional detection methods, leaving the reader to wonder about the potential advantages or limitations of this new approach.

What are the specific rare earth complexes used in the first particles, and how do they contribute to the detection sensitivity of the method?

The article does not delve into the specific rare earth complexes utilized in the first particles, leaving a gap in understanding about their role in enhancing the detection sensitivity of the method.

Original Abstract Submitted

to provide a method and kit for measurement of a target substance with high detection sensitivity, provided is a method of measuring at least any one of the presence or absence, and a concentration, of a target substance in a sample liquid, the method including the steps of: (a) preparing a first particle that specifically binds to the target substance and contains a rare earth complex, and a second particle that has a larger average particle diameter than that of the first particle and specifically binds to the target substance; (b) mixing the sample liquid, the first particle, and the second particle to provide a mixed liquid; and (c) determining at least any one of the presence or absence, and the concentration, of the target substance from polarization anisotropy of the mixed liquid obtained in the step (b).