CHARLES RIVER LABORATORIES, INC. (20240294943). METHOD FOR IMPROVING GENETIC ENGINEERING OF ADOPTIVE CELL THERAPIES simplified abstract
Contents
METHOD FOR IMPROVING GENETIC ENGINEERING OF ADOPTIVE CELL THERAPIES
Organization Name
CHARLES RIVER LABORATORIES, INC.
Inventor(s)
Despina Pleitez of Wilmington MA (US)
Terri Jerbi of Wilmington MA (US)
Jade Scheers of Wilmington MA (US)
Sarah Campion of Wilmington MA (US)
Matthew Hewitt of Wilmington MA (US)
Alex Sargent of Wilmington MA (US)
METHOD FOR IMPROVING GENETIC ENGINEERING OF ADOPTIVE CELL THERAPIES - A simplified explanation of the abstract
This abstract first appeared for US patent application 20240294943 titled 'METHOD FOR IMPROVING GENETIC ENGINEERING OF ADOPTIVE CELL THERAPIES
The present disclosure introduces methods for enhancing the electroporation of cells, particularly those used in cellular-based therapies, to improve cell viability, proliferation, and transfection efficiency. These methods involve the use of a post-electroporation supplement to enhance genetic engineering of the cells.
- Utilizes post-electroporation supplement to improve cell viability, proliferation, and transfection efficiency
- Specifically designed for cells used in cellular-based therapies
- Enhances genetic engineering of cells
- Increases the effectiveness of electroporation in delivering genetic material into cells
- Improves overall cell health and functionality
Potential Applications: - Cell-based therapies - Genetic engineering research - Biotechnology and pharmaceutical industries
Problems Solved: - Low cell viability post-electroporation - Inefficient transfection of genetic material into cells - Limited cell proliferation rates
Benefits: - Enhanced cell viability and proliferation - Improved transfection efficiency - Increased success rates in genetic engineering experiments
Commercial Applications: Title: Enhanced Cell Electroporation Technology for Cellular-Based Therapies This technology could be utilized in the development of novel cell-based therapies, genetic engineering research, and applications in the biotechnology and pharmaceutical industries. The improved efficiency and effectiveness of cell electroporation could lead to advancements in personalized medicine and regenerative therapies.
Questions about Enhanced Cell Electroporation Technology for Cellular-Based Therapies: 1. How does the post-electroporation supplement enhance cell viability and proliferation? The post-electroporation supplement provides essential nutrients and factors that support cell growth and recovery after the electroporation process, leading to increased cell viability and proliferation rates.
2. What are the potential long-term implications of using this technology in genetic engineering research? This technology could revolutionize genetic engineering research by improving the efficiency of delivering genetic material into cells, leading to more accurate and reliable results in experiments.
Original Abstract Submitted
the present disclosure provides methods for electroporating cells, in particular cells useful in cellular-based therapies, that increase cell viability, cell proliferation and transfection efficiency. the methods suitably utilize a post-electroporation supplement to improve the genetic engineering of the various cells.
