Boston scientific scimed, inc. (20240307117). METHODS AND APPARATUS FOR SELECTIVE TISSUE ABLATION simplified abstract

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METHODS AND APPARATUS FOR SELECTIVE TISSUE ABLATION

Organization Name

boston scientific scimed, inc.

Inventor(s)

Steven R. Mickelsen of Iowa City IA (US)

METHODS AND APPARATUS FOR SELECTIVE TISSUE ABLATION - A simplified explanation of the abstract

This abstract first appeared for US patent application 20240307117 titled 'METHODS AND APPARATUS FOR SELECTIVE TISSUE ABLATION

Simplified Explanation: The patent application describes catheter systems and methods for the selective and rapid application of DC voltage to drive irreversible electroporation. An apparatus includes a voltage pulse generator and an electrode controller to deliver a pulsed voltage waveform to a subset of electrodes.

  • **Key Features and Innovation:**
   - Apparatus for selective and rapid application of DC voltage for irreversible electroporation.
   - Voltage pulse generator produces a pulsed voltage waveform.
   - Electrode controller selects a subset of electrodes and delivers the voltage waveform.
   - Identification of electrodes as anode and cathode for effective electroporation.
  • **Potential Applications:**
   - Medical procedures requiring precise and controlled electroporation.
   - Cancer treatment through targeted cell destruction.
   - Research in genetic engineering and cell biology.
  • **Problems Solved:**
   - Enables precise and targeted application of DC voltage for electroporation.
   - Facilitates efficient cell membrane permeabilization for various applications.
  • **Benefits:**
   - Enhanced control and accuracy in electroporation procedures.
   - Increased efficiency in cell membrane permeabilization.
   - Potential for improved outcomes in medical treatments.
  • **Commercial Applications:**
   - Title: "Advanced Catheter Systems for Targeted Electroporation in Medical Procedures"
   - Potential use in oncology for tumor ablation procedures.
   - Market implications in the medical device industry for innovative electroporation technologies.
  • **Prior Art:**
   - Further research can be conducted in the field of electroporation techniques and applications.
   - Existing patents related to electroporation methods and devices may provide additional insights.
  • **Frequently Updated Research:**
   - Ongoing studies on the optimization of electroporation parameters for various medical and research applications.

Questions about Catheter Systems for Electroporation: 1. How does the selective application of DC voltage in electroporation improve treatment outcomes? 2. What are the potential challenges in implementing catheter systems for targeted electroporation in medical procedures?


Original Abstract Submitted

catheter systems and methods for the selective and rapid application of dc voltage to drive irreversible electroporation are disclosed herein. in some embodiments, an apparatus includes a voltage pulse generator and an electrode controller. the voltage pulse generator is configured to produce a pulsed voltage waveform. the electrode controller is configured to be operably coupled to the voltage pulse generator and a medical device including a series of electrodes. the electrode controller includes a selection module and a pulse delivery module. the selection module is configured to select a subset of electrodes from the series of electrodes. the selection module is configured identify at least one electrode as an anode and at least one electrode as a cathode. the pulse delivery module is configured to deliver an output signal associated with the pulsed voltage waveform to the subset of electrodes.

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