BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM patent applications published on July 25th, 2024

Summary of the patent applications from BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM on July 25th, 2024

1. **Summary**: The recent patents filed by the organization involve innovative technologies such as a fission product trap for reactor systems, ER ligands for targeted therapies in hormone-related diseases, enhanced drug-eluting tube devices for pain management, and CAR-T MNP compositions for targeted therapeutic delivery. These patents focus on improving safety, efficacy, and precision in various medical and pharmaceutical applications.

2. **Key Points of Patents**:

  * Fission Product Trap:
    * Utilizes a porous container with an absorbing material to trap fission products.
    * Designed for reactor systems to contain and minimize the release of radioactive materials.
  * ER Ligands:
    * Target specific estrogen receptors for therapeutic benefits.
    * Focus on ERβ selectivity for improved treatments with fewer side effects.
  * Enhanced Drug-Eluting Tube Devices:
    * Deliver analgesics to internal discomfort sites with reloadable drugs and lubricating coatings.
    * Include flexible regions to dampen force transmission to implanted sites.
  * CAR-T MNP Compositions:
    * Utilize engineered T lymphocyte membrane-coated nanoparticles for targeted therapeutic delivery.
    * Enhance precision in drug delivery and reduce side effects.

3. **Notable Applications**:

  * Fission Product Trap:
    * Nuclear power plants, research reactors, and nuclear waste storage facilities.
  * ER Ligands:
    * Treatment of hormone-related conditions like breast cancer and osteoporosis.
  * Enhanced Drug-Eluting Tube Devices:
    * Pain management in medical procedures, post-operative care, and targeted drug delivery.
  * CAR-T MNP Compositions:
    * Targeted drug delivery for cancer, autoimmune disorders, and infectious diseases.

Patent applications for BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM on July 25th, 2024

PRODUCTION OF THERAPEUTIC MESENCHYMAL STEM CELL-DERIVED EXOSOMES (18559667)

Main Inventor

Frederick F. LANG

DOUBLE SIDED CHIMERIC ANTIGEN RECEPTOR (CAR) ENGINEERED CELL MEMBRANE BASED DRUG DELIVERY SYSTEMS (18558882)

Main Inventor

Kytai NGUYEN

DRUG-ELUTING TUBES FOR IMPROVED PATIENT CARE (18566362)

Main Inventor

Daniel Stromberg

INDANONE AND TETRALONEKETO OR HYDROXYL OXIMES AS CANCEL THERAPEUTICS (18558765)

Main Inventor

Stanton McHardy

FISSION PRODUCT TRAP FOR SALT PIPE AND PUMP SHAFT SEALS AND METHODS OF USE THEREOF (18157561)

Main Inventor

Timothy Head