18749553. METHOD FOR LATERAL FLOW IMMUNOASSAY simplified abstract (Purdue Research Foundation)

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METHOD FOR LATERAL FLOW IMMUNOASSAY

Organization Name

Purdue Research Foundation

Inventor(s)

Joseph Irudayaraj of Champaign IL (US)

Wen Ren of Urbana IL (US)

METHOD FOR LATERAL FLOW IMMUNOASSAY - A simplified explanation of the abstract

This abstract first appeared for US patent application 18749553 titled 'METHOD FOR LATERAL FLOW IMMUNOASSAY

The present disclosure introduces a novel method for lateral flow immunoassay (LFIA) using a plasmonic enhancement strategy, specifically focusing on a plasmonic enhanced lateral flow sensor (pLFS) concept with liposome-based colorimetric signal amplification for ultra-sensitive pathogen detection.

  • Utilizes plasmonic enhancement strategy for LFIA
  • Introduces pLFS concept for ultra-sensitive pathogen detection
  • Utilizes liposome-based amplification of colorimetric signals
  • Enhances detection capabilities on lateral flow platform
  • Improves sensitivity and accuracy of pathogen detection

Potential Applications: - Medical diagnostics - Food safety testing - Environmental monitoring - Biodefense and biosecurity

Problems Solved: - Low sensitivity in pathogen detection - Limited accuracy in lateral flow immunoassays - Challenges in detecting pathogens at low concentrations

Benefits: - Enhanced sensitivity for early detection of pathogens - Improved accuracy in pathogen identification - Rapid and reliable results in point-of-care settings

Commercial Applications: Title: "Plasmonic Enhanced Lateral Flow Sensor for Ultra-Sensitive Pathogen Detection" This technology can be utilized in various industries such as healthcare, food safety, environmental monitoring, and biodefense, offering improved pathogen detection capabilities and faster results.

Questions about Plasmonic Enhanced Lateral Flow Sensor for Ultra-Sensitive Pathogen Detection: 1. How does the liposome-based amplification enhance the colorimetric signals in the lateral flow sensor? 2. What are the specific advantages of using a plasmonic enhancement strategy in LFIA?


Original Abstract Submitted

The present disclosure relates to a novel method for lateral flow immunoassay (LFIA) by utilizing plasmonic enhancement strategy. More specifically, the present disclosure provides a plasmonic enhanced lateral flow sensor (pLFS) concept by introducing a liposome-based amplification of the colorimetric signals on the lateral flow platform for ultrasensitive detection of pathogens.