18725244. SYSTEM FOR BODY FLUID ISOMER ANALYSIS (KONINKLIJKE PHILIPS N.V.)

SYSTEM FOR BODY FLUID ISOMER ANALYSIS

Organization Name

KONINKLIJKE PHILIPS N.V.

Inventor(s)

LUTZ CHRISTIAN Gerhardt of Noord-Brabant (NL)

LAURENTIA JOHANNA Huijbregts of EINDHOVEN (NL)

KIRAN HAMILTON J. Dellimore of UTRECHT (NL)

RON MARTINUS LAURENTIUS Van Lieshout of GELDROP (NL)

EDUARD GERARD MARIE Pelssers of LIMBURG (NL)

MARK THOMAS Johnson of ARENDONK (BE)

SYSTEM FOR BODY FLUID ISOMER ANALYSIS

This abstract first appeared for US patent application 18725244 titled 'SYSTEM FOR BODY FLUID ISOMER ANALYSIS

Original Abstract Submitted

A sensor device for measuring levels of one or more stereoisomers in body fluids, for example lactate in sweat. The device includes a body fluid collection means and an optical measurement system. The measurement of the isomer levels is based on measuring an optical property of an incident light which is known to be modified in a reliable and reproducible way by intrinsic optical activity of at least one isomer within the sample. By measuring the optical property, an indication of concentration of at least one stereoisomer can be derived. For example, D- and L-lactate are enantiomers and the optical activity of each has the effect of changing a rotation angle of light polarization. It also has the effect of changing a central frequency of a spectral composition of the incident light. In each case a polarization state modification is applied to the light before or after application to the sample.